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Play once: The default Cue mode, just plays the Cue once and moving forward.
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Loop: This Cue loops by a given number of time between the current and the next Cue (or the Composition Out Time if there are no Cues after it), then continue playback normally. Drawn with light grey colour and it also draws bar that indicates the looping part of the timeline.
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Infinite Loop: This Cue is looping forever whenever it has reached by the playhead.
In general, to break a Looping Cue you either need to disable Cues by the Cue Enable button, or jump to the next Cue.